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. 2022 Jan 24;12(4):1855–1869. doi: 10.7150/thno.69017

Figure 3.

Figure 3

Deletion of endothelial Ppard increases vascular permeability. A (Representative images) and B (quantification) of Evans Blue in quadriceps 14 days after HLI. C, Representative images of FITC-labeled 70 kDa dextran co-stained with CD144 in GA at day 7 after HLI (n = 5, each group). Scale bar: 200 μm. D, Representative images of ZO-1 to co-localize with CD144 in GA at day 10 after HLI (n = 6, each group). Scale bar: 200 μm. Triangle indicates continuous endothelium. Arrowhead indicates discontinuous endothelium. E-J, qPCR analysis of muscles 3 days after HLI (n = 6, each group). Results are means ± SEM. * p < 0.05, ** p < 0.01 between groups by one-way ANOVA and multiple comparison test.