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. 2021 Jan 9;48(1):141–151. doi: 10.1007/s00068-020-01578-9

Table 2.

Patient demographics and relevant outcomes for included studies

Authors Sample size Frailty measure Female N (%) Frail N (%) Relevant outcomes
McGuckin et al. [26] 38 CFS 18 (47) 11 (29)

30-day mortality

Frail patients: 2/11 (18.2%)

Non-frail patients: 1/27 (3.7%)

Unadjusted OR = 5.78

Length of stay

Frail patients: mean 54.2 days (SD = 77.3)

Non-frail patients: mean 38.3 days (SD = 54.0)

Tan et al. [27] 109 MFI 51 (47) 22 (20)

Loss of functional independence at 1 year

Compare to patients with MFI 1–2, patients with MFI ≥ 3 has an unadjusted OR 4.42 for the outcome

Complications

Frail patients: 1/22 (4.5%)

Non-frail patients: 6/87 (6.9%)

Unadjusted OR = 0.64

Length of stay

Frail patients: mean 15.5 days (SD = 9.6)

Non-frail patients: mean 14.3 days (SD = 9.7)

Parmar et al. [28] 937 CFS 540 (58) 190 (20)

90-day mortality

Frail patients: 62/189 (32.8%)

Non-frail patients:121/741 (16.3%)

Unadjusted OR = 2.50

Compare to patients with CFS = 1, the adjusted ORs were 0.84, 1.38, 3.15, 3.18, 6.10 for CFS 2, 3, 4, 5 and 6–7(adjusted for age and sex)

30-day mortality

Frail patients: 50/190 (26.3%)

Non-frail patients: 87/747 (11.6%)

Unadjusted OR = 2.71

Compare to patients with CFS = 1, the adjusted ORs were 2.05, 3.11, 7.49, 9.79 and 10.40 for CFS 2, 3, 4, 5 and 6–7 (adjusted for age and sex)

Length of stay

Compare to patients with CFS = 1, the adjusted ORs were 1.21, 1.26, 1.48, 1.44 and 1.62 for CFS 2, 3, 4, 5 and 6–7

Carter et al. [29] 934 CFS 538 (58) 189 (20)

Increased level of care

Frail patents: 101/189 (53.4%)

Non-frail patients: 248/745 (33.3%)

Unadjusted OR 2.30

Compare to patients with CFS = 1, the adjusted ORs were 2.14, 1.84, 4.48, 5.94 and 7.88 for CFS 2, 3, 4, 5 and 6–7 (adjusted for sex, age and care level before admission)

Length of stay

Compared to patients with CFS = 1, the adjusted HRs were 0.74, 0.66, 0.50, 0.52 and 0.55 for CFS 2, 3, 4, 5 and 6–7 (adjusted for sex, age and care level before admission)

Arteaga et al. [30] 92 CFS 49 (53) 23 (25)

30-day mortality

Frail patients: 6/23 (26.1%)

Non-frail patients: 4/69 (5.8%)

Unadjusted OR = 2.71

Complications

Frail patients: 9/23 (39.1%)

Non-frail patients: 11/69 (15.9%)

Unadjusted OR = 3.39

Vilches-Moraga et al. [31] 113 CFS 60 (53) 37 (33)

1-year mortality

Frail patients: 22/37 (59.5%)

Non-frail patients: 22/76 (28.9)

Unadjusted OR 3.60

Compare to non-frail patients, frail patients had an adjusted HR of 5.40 (adjusted for ASA, reduced mobility and, peri-operative geriatric team)

MFI Modified Frailty Index, OR Odds Ratio, CFS Clinical Frailty Scale, HR Hazard Ratio