FIGURE 7.

Effect of SCFAs on phosphorylation of NF‐κB p65, JNK1/2, and ERK1/2 in IL‐1β‐induced FHs 74 Int cells. FHs 74 Int cells were pretreated with or without acetate (a, 20 mM), propionate (b, 20 mM), or butyrate (c, 20 mM) for 1 h, and then induced by IL‐1β (0.5 ng/ml) for 24 h. The protein bands were detected by Western blot (a) and the band densities were quantified (b). Data are represented as mean ± SD. ^∗ p < .05, ^∗∗ p < .01, ^∗∗∗ p < .001 vs. the IL‐1β group. ^# p < .05, ^## p < .01, ^### p < .001 vs. the control group