Table 1.
Timeline of patient clinical history.
October 2006 | Memory loss and headaches |
---|---|
November 2006 | MRI: 35 ×26 mm infra and supra-sellar mass, pressing on third ventricule and interpeduncular cistern |
December 2006 | Transcranial fronto temporal escision |
January → March 2007 | Adjuvant radiotherapy 50 Gy |
2007 → 2013 | FUP (discontinued voluntarily in 2013) |
November 2019 | Vertigo, unsteady gait, lipothymia CT scan: 19 ×23 mm infra and supra-sellar mass MRI: 25 ×38 ×23 mm, extending to chiasmatic and interpenducolar cisterns and pavement of the third ventricle |
January 2020 | Endonasal endoscopic exeresis |
February 2020 | MRI: 19 ×22 ×19 mm residual mass |
February 2020 | Treatment start: Dabrafenib 300 mg/day + Trametinib 2 mg/day |
June 2020 | Partial response showed at MRI: 14 ×9 ×5 mm mass (>35% reduction) |