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. 2022 Feb 8;12:2062. doi: 10.1038/s41598-021-04330-4

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Expression of miR-125a and ET1 mRNA/protein in SH-SY5Y cells was influenced by the transfection of miR-125a precursors or ET1 siRNA. (A) Relative expression of miR-125a in SH-SY5Y cells was elevated after the transfection with miR-125a precursors, while the transfection of ET1 siRNA exhibited no evident effect on the expression of miR-125a; (B) Relative expression of ET1 mRNA in SH-SY5Y cells was evidently suppressed after the transfection with miR-125a precursors or ET1 siRNA; (C) Relative expression of ET1 protein in SH-SY5Y cells was significantly lower after the transfection with miR-125a precursors or ET1 siRNA.