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. 2022 Feb 8;9:8. doi: 10.1186/s40580-022-00299-6

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Impedance analysis in a human gut-on-a-chip. Impedance spectra showing the development of an intestinal epithelial barrier cultured with A Caco-2 cell only and B co-culture with Caco-2 cells and HUVECs. C Epithelial resistance with respect to culture days, showing that the resistance of the co-culture model was increased with culture days. D Epithelial impedance versus calculated TEER analysis in the co-cultured model