Figure 4.
Effect of late-onset HIF-1α increase on astrocyte activation and gliosis. (A) Representative picture of immunofluorescence stained with CS-56 (CSPGs marker) (green) and GFAP (red) in the ipsilateral corpus callosum. (B) Quantification of GFAP intensity at 14 d post injury after late HIF-1α inhibition. (C) Quantification of CSPGs intensity at 14 d post injury after late HIF-1α inhibition. Scale bar: 100 µm; n=3–4/group. Values were shown as mean ± SEM; *, P<0.05; **, P<0.01 by ANOVA followed by Tukey’s post hoc test.