Table 5. Chromosomal abnormalities detected by ultrasound soft markers.
| Ultrasonographic abnormal marker | n | NIPT high risk | Abnormal karyotypes | Rate of abnormal karyotypes |
|---|---|---|---|---|
| Single soft marker | ||||
| NT/NF thickening | 19 | 2 | 1 | |
| Single umbilical artery | 5 | 0 | 0 | |
| Mild dilatation of the lateral ventricles | 5 | 0 | 0 | |
| Choroid plexus cysts in the lateral ventricles | 4 | 2 | 2 | |
| Bright spots in the ventricles | 32 | 11 | 3 | |
| Echo enhancement of the intestinal canal | 5 | 1 | 0 | |
| Renal pelvis dilation | 10 | 1 | 0 | |
| Nasal bone hypoplasia or absence | 15 | 4 | 2 | |
| Short femur | 11 | 1 | 0 | |
| Total | 106 | 22 | 8 | 7.55% (8/106) |
| Two soft markers | 40 | 8 | 5 | 12.50% (5/40) |
| Three or more soft markers | 6 | 3 | 1 | 16.67% (1/6) |
NT, nuchal translucency thickness; NF, nuchal fold; Notes: NIPT, noninvasive prenatal testing.