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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Glia. 2021 Dec 28;70(4):697–711. doi: 10.1002/glia.24134

Figure 8.

Figure 8

Spatial overlap of GAD-defined modules (green) and CX3CL1 expression (red) at P12. In keeping with MGC recruitment into modular zones at this age as observed in CX3CR1+/GFP mice with functional fractalkine receptors, earlier unremarkable expression of fractalkine becomes distinctly modular at P12 (a-c). Higher magnifications (d-f) of inset box (a) show clear overlap of fractalkine expression and GAD-positive LCIC modules. While spatially aligned (i.e. modular), CX3CL1- and GAD-positive neuronal populations appear largely distinct, with few double-labeled cells (f). Scale bars (a-c) = 100µm and (d-f) = 50µm.