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. 2022 Jan 26;13:768325. doi: 10.3389/fphar.2022.768325

TABLE 1.

Trends in expenditure for OMPs and cumulative number of rare disease patients treated with OMPs per year.

Year % For OMPs from expenditure for all medicines % Of exceptionally reimbursed OMPs from expenditure for all OMPs Cumulative number of patients treated with accessible OMPs Cumulative number of patients treated with exceptionally reimbursed OMPs Cumulative number of patients treated with OMPs
2010 2.8 2.2 1,405 44 1,449
2011* 3.4 4.7 1,739 72 1,811
2012 3.7 8.1 1,781 58 1,832
2013 3.2 17.2 1,375 108 1,483
2014 3.6 17.2 1,527 152 1,679
2015 3.7 23.4 1,552 231 1,783
2016 4.2 27.0 1,583 295 1,878
2017 4.2 20.8 1,635 309 1,944
2018** 4.7 15.0 1,873 309 2,182
2019** 5.3 14.2 1,926 271 2,197

* New pricing and reimbursement Act, ** Novelization of the pricing and reimbursement Act.