Figure 3. Characteristics and Outcomes of Children Hospitalized With Multisystem Inflammatory Syndrome in Children (MIS-C) vs Acute COVID-19.

Comparison of the percentage of hospitalized children with MIS-C (identified via the presence of qualifying International Statistical Classification of Diseases, 10th Revision code) and acute COVID-19 (positive SARS-CoV-2 PCR/Ag but no positive antibody test or MIS-C International Statistical Classification of Diseases, 10th Revision code) with a given demographic characteristic, preexisting comorbidity, abnormal laboratory test value (during hospitalization), or clinical outcome. eTable 7 in the Supplement provides the absolute number of patients in each corresponding category. Per National COVID Cohort Collaborative policy, groups with fewer than 20 patient encounters were censored and are reported as 0%. ALC indicates absolute lymphocyte count; ALT, alanine aminotransferase; ANC, absolute neutrophil count; BNP, brain-type natriuretic peptide; ECMO, extracorporeal membrane oxygenation; ESR, erythrocyte sedimentation rate; IL-6, interleukin 6; Na, sodium; NT-Pro-BnP, N-terminal pro b-type natriuretic peptide; PCCC, pediatric complex chronic condition; PCR/Ag, polymerase chain reaction/antigen; and WBC, white blood cell. To convert ALC to ×10⁹ per liter, multiply by 0.001; ALT to microkatals per liter, multiply by 0.0167; ANC to ×10⁹ per liter, multiply by 0.001; BNP to nanograms per liter, multiply by 1; ferritin to micrograms per liter, multiply by 1; and Na to millimoles per liter, multiply by 1.

^aThe percentage of children with obesity was calculated by dividing the number of children aged 2 years or older with a body mass index (for age and sex) greater than or equal to the 95th percentile by the number of children in that subgroup who were aged 2 years or older and had a body mass index measurement available.