FIGURE 2.

The effect of SHI on ECM1/STAT5/NF-κB signaling in CLP-induced mice. The mice were intragastrically treated with drugs 2 h before the surgery, and at 0, 2, 12 h after the CLP surgery, respectively. The neutrophils were stained by anti-Ly6G-PE, while the macrophages were stained by anti-F4/80-FITC. (A,B) The effect of SHI on the populations of neutrophils and macrophages in the BALF were detected by flow cytometry. (C–J) The protein expressions of ECM1, p-STAT5, STAT5, p-NF-κB, NF-κB, Arg1, CD206, CD16/32, and iNOS in lung tissues. The data are expressed as mean ± SD. Compared with sham: ^#p < 0.05, ^## p < 0.01. Compared with CLP: *p < 0.05, **p < 0.01.