Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic diagram of the role of Piezo1 in chronic bladder inflammation. The ICC-LC in the bladder senses mechanical stimulation and works in reverse with NCX to trigger the continuous flow of Ca2+ into the ICC-LC, leading to Ca2+ overload and ICC-LC dysfunction and inducing bladder function abnormalities and inflammation.
