Table 5.
Microbiological Impact
| Type of Culture | Control Group (n = 149) | ECIL-4 Group (n = 233) | P Value |
|---|---|---|---|
| Blood cultures | |||
| Gram-positive | 73/149 (49.0) | 98/233 (42.1) | .184 |
| Streptococcus viridans | 26/73 (35.6) | 28/98 (28.6) | |
| CoNS | 20/73 (27.4) | 27/98 (27.6) | |
| Enterococcus faecium | 10/73 (13.7) | 19/98 (19.4) | |
| Staphylococcus aureus | 7/73 (9.6) | 14/98 (14.3) | |
| Other gram-positive | 10/73 (13.7) | 10/98 (10.2) | |
| Quinolone resistant | 12/73 (16.4) | 29/98 (29.6) | |
| MRSA | 1/7 (14.3) | 1/14 (7.1) | |
| Methicillin-resistant CoNS | 11/20 (55.0) | 21/27 (77.8) | .098 |
| Vancomycin-resistant enterococci | 1/10 (10.0) | 0/19 (0.0) | |
| Gram-negative | 76/149 (51.0) | 135/233 (57.9) | .184 |
| Escherichia coli | 47/76 (61.8) | 71/135 (52.6) | |
| Klebsiella species | 7/76 (9.2) | 28/135 (20.7) | |
| Pseudomonas species | 7/76 (9.2) | 12/135 (8.9) | |
| Other gram-negative | 15/76 (19.7) | 24/135 (17.8) | |
| Multidrug susceptible | 51/76 (67.1) | 93/135 (68.9) | |
| Quinolone resistant | 9/76 (11.8) | 11/135 (8.1) | |
| Multidrug resistant | 5/76 (6.6) | 4/135 (3.0) | |
| Stool cultures | Control group (n = 512) | ECIL-4 group (n = 446) | |
| CPE | 1 (0.2) | 4 (0.9) | |
| Vancomycin-resistant enterococci | 16 (3.1) | 1 (0.2) | <.001 |
| Clostridioides | 15 (2.9) | 12 (2.7) | |
Data are presented as No. (%) unless otherwise indicated.
Abbreviations: CoNS, coagulase-negative staphylococci; CPE, carbapenemase-producing Enterobacteriaceae; ECIL-4, Fourth European Conference on Infections in Leukaemia; MRSA, methicillin-resistant Staphylococcus aureus.