Table 1.
Specific detection of HBV-DNA, cccDNA, HBsAg and HBcrAg in the sera and livers of 6 selected patients.
| ID | Age | Sex | HBV DNA (log copies/mL) | Anti-HBc | HBsAg (IU/mL) | HBeAg/anti-HBe | HBcrAg (LogU/mL) | Intrahepatic cccDNA (copies/1000 ng) | Intrahepatic RPP30 (copies/1000 ng) | Intrahepatic cccDNA (copies/cell) | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Non-tumor | Tumor | Non-tumor | Tumor | Non-tumor | Tumor | ||||||||
| 1 | 60 | M | – | + | – | −/− | < 3 | n.d | n.d | 82,450 | 51,650 | – | – |
| 2 | 71 | M | – | + | 9.2 | −/+ | < 3 | n.d | 5.0 | 36,100 | 79,400 | – | 0.00013 |
| 3 | 59 | M | 4.1 | + | > 2000 | −/+ | 6.76–8.74 | 1095 | 37,280 | 43,100 | 63,200 | 0.05081 | 1.17975 |
| 4 | 55 | M | < 2.1 | + | 814.1 | −/+ | 4.6 | 511 | 48,590 | 109,500 | 104,000 | 0.00933 | 0.93442 |
| 5 | 70 | M | – | + | – | −/− | < 3 | n.d | n.d | 62,800 | 60,500 | – | – |
| 6 | 78 | M | – | − | – | −/− | < 3 | – | 3.0 | 42,600 | 70,500 | – | 0.00009 |