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. 2022 Feb 8;13(2):125. doi: 10.1038/s41419-022-04577-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — RAW264.7 macrophage cells were transfected with G0S2 siRNA or G0S2 plasmid plus with LPS 1 μg/ml or IL-4 20 ng/ml treatment for 24 h. A, C, I, and K Representative FCM analysis the ration of M1 (CD11C⁺ cells vs. F4/80 cells). B, F, J, and N Representative FCM analysis the ration of M2 (CD206⁺ cells vs. F4/80 cells). D and L The expression levels of TNF-α were detected by real-time qPCR. E and M The expression levels of IL-1β were detected by real-time qPCR. G and O The expression levels of TGF-β1 were detected by real-time qPCR. H and P The expression levels of Arg1 were detected by real-time qPCR. ^#P < 0.05 versus Scramble plus LPS or IL-4 group. Data are expressed as means ± sd (n = 6). *P < 0.05 versus LPS and IL-4 group.