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. 2022 Feb 8;13:731. doi: 10.1038/s41467-022-28417-2

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Fig. 7 — a L151 in ICL2 is inserted into the hydrophobic pocket at the end of the N-terminal helix of Gα_i, and N153 forms hydrogen bonds with D350 and N347 from the α5 helix of Gα_i. b L235 and F237 in ICL3 contact the hydrophobic surface of Gα_i, and K250 forms a salt bridge with D341 from the α5 helix of Gα_i. R321 located at TM5 stretches to the amino-end of TM3 helix and interacts with the carbonyl backbone through hydrogen bonding.