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. 2022 Feb 10;376:e066982. doi: 10.1136/bmj-2021-066982

Table 2.

Salt intake (as calculated from 24 hour urinary sodium excretion), other 24 hour urinary measurements, and blood pressure based on intention-to-treat analysis

Control Intervention Difference (95% CI) in change (intervention v control)†, P value Adjusted difference (95% CI) in change†‡ (intervention v control), P value
No of participants Baseline mean (SD) 12 month
mean (SD)
Change* (95% CI) No of participants Baseline mean (SD) 12 month
mean (SD)
Change* (95% CI)
Children
Salt intake (g/day) 294 5.6 (2.1) 6.1 (2.3) 0.52 (0.26 to 0.78) 296 5.5 (1.9) 5.7 (2.3) 0.19 (−0.07 to 0.44) −0.33 (−0.69 to 0.03) 0.07 −0.25 (−0.61 to 0.12) 0.18
Systolic blood pressure (mm Hg) 295 92.5 (9.8) 95.3 (8.7) 2.65 (1.53 to 3.77) 297 92.8 (9.7) 94.3 (9.9) 1.46 (0.36 to 2.56) −1.19 (−2.76 to 0.38) 0.14 −0.76 (−2.37 to 0.86) 0.36
Diastolic blood pressure (mm Hg) 295 64.0 (8.2) 65.5 (7.4) 1.40 (0.43 to 2.37) 297 64.3 (8.5) 64.5 (7.8) 0.12 (−0.83 to 1.08) −1.28 (−2.64 to 0.09) 0.07 −1.05 (−2.45 to 0.34) 0.14
Urinary sodium
(mmol/24 hours)
294 95.3 (35.0) 104.3 (39.0) 8.88 (4.49 to 13.27) 296 94.1 (33.2) 96.9 (38.6) 3.16 (−1.16 to 7.48) −5.72 (−11.88 to 0.44) 0.07 −4.23 (−10.46 to 2.00) 0.18
Urinary potassium
(mmol/24 hours)
294 24.5 (8.0) 25.0 (8.3) 0.55 (−0.62 to 1.72) 296 24.3 (7.9) 25.1 (8.5) 0.75 (−0.41 to 1.90) 0.20 (−1.44 to 1.84) 0.81 0.29 (−1.39 to 1.98) 0.73
Sodium-to-
potassium ratio
294 4.2 (1.8) 4.5 (2.0) 0.27 (0.02 to 0.53) 296 4.2 (1.7) 4.3 (2.3) 0.10 (−0.15 to 0.35) −0.17 (−0.53 to 0.19) 0.35 −0.10 (−0.46 to 0.27) 0.61
Urinary creatinine
(mmol/24 hours)
294 4.9 (1.3) 5.3 (1.2) 0.31 (0.19 to 0.44) 296 4.8 (1.2) 5.2 (1.3) 0.45 (0.33 to 0.58) 0.14 (−0.04 to 0.32) 0.13 0.14 (−0.04 to 0.33) 0.13
Urine volume
(mL/24 hours)
294 812.5 (287.6) 895.5 (329.7) 79.05 (38.58 to 119.52) 296 877.4 (303.7) 926.8 (355.1) 47.04 (7.23 to 86.86) −32.01 (−88.78 to 24.77) 0.27 −16.86 (−75.00 to 41.28) 0.57
Adults
Salt intake (g/day) 587 10.0 (3.6) 9.8 (3.9) −0.30 (−0.59 to −0.01) 593 10.0 (3.5) 8.9 (3.2) −1.18 (−1.47 to −0.89) −0.88 (−1.29 to −0.47) <0.001 −0.82 (−1.24 to −0.40) <0.001
Systolic blood pressure (mm Hg) 590 118.9 (16.8) 118.5 (17.5) −0.32 (−1.29 to 0.65) 594 118.7 (17.6) 115.7 (16.5) −2.86 (−3.81 to −1.90) −2.53 (−3.90 to −1.17) <0.001 −1.64 (−3.01 to −0.27) 0.02
Diastolic blood pressure (mm Hg) 590 77.5 (10.2) 76.6 (11.0) −0.82 (−1.50 to −0.14) 594 76.9 (10.6) 74.7 (9.9) −2.01 (−2.68 to −1.34) −1.19 (−2.15 to −0.23) 0.02 −0.48 (−1.44 to 0.48) 0.33
Urinary sodium
(mmol/24 hours)
587 171.6 (62.1) 167.6 (66.1) −5.17 (−10.15 to −0.18) 593 171.7 (60.3) 151.6 (54.2) −20.17 (−25.05 to −15.28) −15.00 (−21.98 to −8.03) <0.001 −14.02 (−21.20 to −6.83) <0.001
Urinary potassium
(mmol/24 hours)
587 39.9 (13.8) 39.6 (13.4) −0.52 (−1.68 to 0.64) 593 39.4 (13.2) 39.3 (13.6) −0.38 (−1.52 to 0.76) 0.14 (−1.49 to 1.76) 0.87 0.15 (−1.53 to 1.83) 0.86
Sodium-to-
potassium ratio
587 4.6 (1.8) 4.5 (1.8) −0.10 (−0.25 to 0.05) 593 4.6 (1.7) 4.2 (1.8) −0.40 (−0.54 to −0.25) −0.30 (−0.50 to −0.09) 0.005 −0.27 (−0.48 to −0.06) 0.01
Urinary creatinine
(mmol/24 hours)
587 11.0 (3.2) 10.4 (3.0) −0.57 (−0.73 to −0.41) 593 10.7 (3.1) 10.3 (3.0) −0.48 (−0.64 to −0.32) 0.09 (−0.14 to 0.31) 0.45 0.05 (−0.18 to 0.28) 0.66
Urine volume
(mL/24 hours)
587 1529.6 (593.9) 1491.6 (536.2) −48.55 (−93.62 to −3.49) 593 1598.9 (582.1) 1556.3 (530.5) −54.27 (−98.46 to −10.08) −5.72 (−68.84 to 57.40) 0.86 36.80 (−27.48 to 101.08) 0.26

SD=standard deviation.

*

Comparison of the means between baseline and 12 month follow-up. Positive values=increases from baseline to 12 month follow-up; negative values=reductions from baseline to 12-month follow-up.

Comparison between intervention and control groups in the changes from baseline to 12 month follow-up. Positive values=the intervention group had a greater increase or less decrease from baseline to 12 month follow-up than the control group; negative values=the intervention group has a greater decrease or smaller increase from baseline to 12 month follow-up than the control group.

Adjusted for age, sex, body mass index (body weight in children instead), outdoor temperature, study site, highest education level in the family; blood pressure values were further adjusted for physical activity and alcohol consumption in adults only.