. Author manuscript; available in PMC: 2022 Aug 1.

Published in final edited form as: Nat Protoc. 2021 Jul 7;16(8):4031–4067. doi: 10.1038/s41596-021-00575-5

Table 2. Top 10 gene sets (with fewer than 100 genes) contributing to cell type replicability.

The “go_term” column shows the identifier, name, and sub-ontology (BP=Biological Process, CC=Cellular Component) of the investigated gene set. Columns “Lamp5” to “Vip” show the replicability (average AUROC over cross-dataset-validation folds) for each cell type and gene set combination. The “average” column takes the average across cell types, “n_genes” shows the number of genes in the gene set.

go_term	Lamp5	Pvalb	Sncg	Sst	Sst.Chodl	Vip	average	n_genes
GO:0007215\|glutamate receptor signaling pathway\|BP	0.97	0.98	0.97	0.98	1.00	0.99	0.98	92
GO:0051966\|regulation of synaptic transmission, glutamatergic\|BP	0.96	0.97	0.98	0.96	0.99	0.97	0.97	75
GO:0060076\|excitatory synapse\|CC	0.96	0.97	0.99	0.96	0.99	0.96	0.97	75
GO:0033555\|multicellular organismal response to stress\|BP	0.95	0.98	0.98	0.95	1.00	0.98	0.97	98
GO:0098839\|postsynaptic density membrane\|CC	0.92	0.97	0.98	0.98	0.98	0.97	0.97	93
GO:0099565\|chemical synaptic transmission, postsynaptic\|BP	0.97	0.98	0.97	0.95	0.99	0.96	0.97	91
GO:0008306\|associative learning\|BP	0.97	0.98	0.96	0.96	0.99	0.95	0.97	100
GO:0099601\|regulation of neurotransmitter receptor activity\|BP	0.96	0.98	0.96	0.95	0.99	0.98	0.97	61
GO:0060079\|excitatory postsynaptic potential\|BP	0.97	0.98	0.97	0.95	0.99	0.95	0.97	83
GO:0010771\|negative regulation of cell morphogenesis involved in differentiation\|BP	0.98	0.98	0.97	0.96	0.99	0.92	0.97	98