Figure 3.

Frequency of loss of heterozygosity according to homologous recombination status. Results for (A) MSS/pMMR population and (B) MSI-H/dMMR population are shown. LOH percentage were compared with the Mann-Whitney test and a 2-sided P value calculated; q values were calculated using the Benjamini-Hochberg method. dMMR = deficient mismatch repair; HRD = homologous recombination deficiency; HRP = homologous recombination proficient; LOH = loss of heterozygosity; MSI-H= microsatellite instability-high; MSS = microsatellite stable; pMMR = proficient mismatch repair.