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. Author manuscript; available in PMC: 2022 Feb 9.
Published in final edited form as: Expert Rev Vaccines. 2017 Dec 29;17(2):145–161. doi: 10.1080/14760584.2018.1418665

Table 6.

Probiotic supplementation by rotavirus vaccine IgA seroconversion.

Reference Location Income groupb Vaccine No of Doses Measured outcomes Supplementation with LGG®
p-Value
Yes No
Lazarus et al. 2017 [127] India LM RV1 2 IgA seroconversion rate 39%a 27% 0.04
Isolauri et al. 1995 [128] Finland H RRV-S1 1 IgA seroconversion rate 93% 74% 0.05

RV1: rotarix; RRV-S1: rhesus-human reassortant monovalent serotype 1; LGG®: Lactobacillus rhamnosus.

a

With additional zinc supplementation.

b

World Bank list of economies (December 2016) low-income (L); lower middle-income (LM); upper middle-income (UM); high-income (H).