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. Author manuscript; available in PMC: 2022 Feb 9.
Published in final edited form as: Expert Rev Vaccines. 2017 Dec 29;17(2):145–161. doi: 10.1080/14760584.2018.1418665

Table 8.

Environmental enteropathy biomarkers by rotavirus vaccine IgA seroconversion.

Reference Location Income
groupa
Vaccine No of
Doses
Measured factors Rotavirus vaccines IgA
seroconversion
p-Value
R NR
Naylor et al. 2015 (153) Bangladesh LM RV1 2 Biomarker of EE (fecal alpha-1-antitrypsin), R2 0.24 *
Becker-Dreps et al. 2017 (154) Nicaragua LM RV5 1 4 Biomarkers of EE, median combined score (IQR) 4.5 (2.8–5.8) 6.5 (4.5–9.5) 0.017

R: responders; NR: non responders; NS: non-statistically significant (p > 0.05); EE: environmental enteropathy; RV1: rotarix; RV5: rotateq.

*

No reported but significant.

a

World Bank list of economies (December 2016) low-income (L); lower middle-income (LM); upper middle-income (UM); high-income (H).