Table 9.

Rotarix response in HIV-exposed and HIV-unexposed-uninfected infants.

Reference	Location	Income groupd	Vaccine	No of doses	Measured factors	HIV-uninfected infantsa		p-Value
						HIV-exposed	HIV-unexposed
Gastanaduy et al. 2016 [35]	Botswana	UM	RV1	2	Effectivenessb after 1 or 2 years (95% CI)	32 (−121, 79)	44 (−34, 76)	NS
Groome et al. 2014 [155]	South Africa	UM	RV1	1	Effectivenessc after 1 or 2 years (95% CI)	61 (22,81)	24 (−17, 51)	NS
				2		64 (34, 80)	54 (31, 69)
Chilengi et al. 2016 [56]	Zambia	LM	RV1	2	IgA seroconversion rate	54%	62%	NS

HIV: human immunodeficiency virus; NS: non-statistically significant (p > 0.05).

^aAn HIV-uninfected child was judged to be HIV-exposed if the mother gave history of testing HIV positive during pregnancy, or HIV-unexposed if the mother had a history of negative HIV test during pregnancy.

^bAgainst severe RVGE;

^cAgainst any RVGE;

^dWorld Bank list of economies (December 2016) low-income (L); lower middle-income (LM); upper middle-income (UM); high-income (H).