Figure 3.

Inducible Slc4a11 KO disrupts the endothelial barrier function. A. Tight and adherens junction gene expression (same conditions as Figure 2B). B. Representative image of ZO-1 and F-actin. C. Endothelial fluorescein permeability; mean ± SEM, n = 4 for Ctrl and Tm, n = 2 for EGTA, **P < 0.01. All conditional KO data is after eight weeks of Tm treatment.