Table 3.

Univariate and multivarite cox proportional hazards analyses for the primary endpoint according to the MHR tertiles.

Variables	Univariate analysis			Multivariate analysis
	HR	95% CI	P -value	HR	95% CI	P -value
MHR tertiles
T1	Reference			Reference
T2	1.54	1.16–2.04	0.003	1.45	1.08–1.95	0.013
T3	2.03	1.55–2.67	<0.001	1.76	1.30–2.40	<0.001
hs-CRP	1.03	1.02–1.05	<0.001	1.02	1.00–1.04	0.03
Sex	1.03	0.80–1.32	0.848	0.70	0.52–0.93	0.015
Smoking	1.15	0.93–1.41	0.200	1.24	0.97–1.59	0.089
Hypertension	1.06	0.85–1.32	0.592	1.07	0.84–1.36	0.589
Diabetes	1.51	1.22–1.86	<0.001	1.31	1.05–1.63	0.016
Dyslipidemia	1.32	1.00–1.75	0.051	0.98	0.72–1.32	0.876
Previous MI	1.55	1.23–1.97	<0.001	1.12	0.85–1.47	0.418
Previous PCI	1.59	1.26–2.00	<0.001	1.44	1.09–1.91	0.01
previous CVA	1.09	0.71–1.68	0.703	0.62	0.39–0.97	0.035
PAD	2.74	2.12–3.54	<0.001	2.28	1.70–3.06	<0.001
Type of ACS
Unstable angina	Reference			Reference
NSTEMI	1.24	0.92–1.67	0.155	1.15	0.78–1.71	0.489
STEMI	1.06	0.78–1.45	0.717	1.24	0.76–2.02	0.396
GRACE risk score	1.00	1.00–1.01	0.05	1.00	0.99–1.00	0.317
SYNTAX score	1.03	1.03–1.04	<0.001	1.02	1.01–1.03	0.005
Complete revascularization	0.43	0.35–0.53	<0.001	0.54	0.42–0.68	<0.001
Aspirin at discharge	0.24	0.13–0.46	<0.001	0.54	0.42–0.68	0.031
ACEI/ARBs at discharge	1.12	0.91–1.38	0.287	0.95	0.76–1.20	0.675
β-blockers at discharge	0.76	0.61–0.95	0.016	0.61	0.49–0.77	<0.001

HR, hazard ratio; CI., confidential interval. Other abbreviations as in Table 1.