Table 4.
Model performance after the addition of MHR to the GRACE risk score for predicting clinical outcomes.
| C-statistic | P -value | cNRI (95% CI) | P -value | IDI(95% CI) | P -value | |
|---|---|---|---|---|---|---|
| Primary endpoint | ||||||
| GRACE score | 0.525 | <0.001 | Ref | <0.001 | Ref | <0.001 |
| GRACE score + MHR | 0.590 | 0.136 (0.062–0.195) | 0.006 (0.001–0.018) | |||
| Death or MI | ||||||
| GRACE score | 0.605 | 0.003 | Ref | 0.218 | Ref | 0.832 |
| GRACE score + MHR | 0.648 | 0.082 (−0.035–0.200) | 0.000 (−0.001–0.008) | |||
| Death, stroke, or MI | ||||||
| GRACE score | 0.622 | 0.023 | Ref | 0.297 | Ref | 0.495 |
| GRACE score + MHR | 0.667 | 0.075 (−0.032–0.175) | 0.001 (−0.001–0.013) | |||
MHR, monocyte to HDL-C ratio; GRACE, Global registry of acute coronary events; MI, myocardial infarction; cNRI, category-free continuous net reclassification improvement; IDI, integrated discrimination improvement; CI, confidential interval.