Skip to main content
. 2022 Jan 26;9:806966. doi: 10.3389/fmolb.2022.806966

FIGURE 5.

FIGURE 5

In vitro interference of miR-135b reduces ranolazine inhibition of cardiac fibrosis. (A–C) Immunofluorescence detection of TGF-β1, collagen I and collagen III expression in cardiac fibroblasts in the groups. (D–F) Real-time PCR was performed to detect the relative mRNA expression of TGF-β1, collagen I and collagen III in groups of cardiac fibroblasts. (G–I) Western blot analysis was performed to detect the relative protein expression of TGF-β1, collagen I and collagen III in cardiac fibroblasts. *** p < 0.001 vs. NG + AMO-NC, ### p < 0.001 vs. HG + AMO-NC, $ p < 0.05 vs. HG + Ran + AMO-NC, $$ p < 0.01 vs. HG + Ran + AMO-NC; n = 3.