Table 2.
Unadjusted and adjusted associations between mean delivered UF rate and incident atrial fibrillation a
| HR (95% CI) |
|||
|---|---|---|---|
| Modelb | UF rate >13 (versus ≤13 mL/h/kg) | UF rate >10 (versus ≤10 mL/h/kg) | UF rate >8 (versus ≤8 mL/h/kg) |
| 0 | 1.21 (1.10–1.31) | 1.08 (1.00–1.15) | 1.08 (1.01–1.15) |
| 1 | 1.22 (1.12–1.33) | 1.10 (1.02–1.17) | 1.10 (1.03–1.17) |
| 2 | 1.22 (1.11–1.32) | 1.09 (1.02–1.17) | 1.10 (1.03–1.17) |
| 3 | 1.16 (1.06–1.27) | 1.06 (0.99–1.14) | 1.08 (1.01–1.15) |
| 4 | 1.15 (1.04–1.25) | 1.06 (0.99–1.14) | 1.09 (1.02–1.16) |
Extended Cox models with multiple imputation for missing data were used to compute adjusted HRs and 95% CIs for the association of each delivered UF rate exposure and incident atrial fibrillation. All models were stratified by year of incident end-stage kidney disease.
Model 0, unadjusted; Model 1, additionally adjusted for age, sex, race and Hispanic ethnicity; Model 2, additionally adjusted for census division, socioeconomic status variables and Medicare/Medicaid dual eligibility; Model 3, additionally adjusted for all comorbid conditions listed in Table 1, number of hospital days in 30 days prior to UF rate ascertainment period and vascular access type; Model 4, additionally adjusted for predialysis systolic and diastolic BP, number of dialysis sessions during UF rate ascertainment period and serum albumin, eGFR, potassium and calcium.