FIG 1.
Evaluation of CpG ODNs as potential adjuvants for 4pox DNA vaccination in rabbits. (A) The number of IgM+/IgG+ splenocytes (“cell number × 103”) was determined 5 days after stimulation with individual CpG oligodeoxynucleotides numbered 1 to 6 (x axis) by flow cytometry. (B) Supernatants were analyzed by ELISA to determine titers of secreted IgG. O.D. optical density. Results are representative of three independent experiments. Symbols represent the mean ± standard error from each group. *, P < 0.05 by t test.