TABLE 2.
Biological characteristics of CSF
| Variable | NS patients (n = 27) | Control patients (n = 71) | NS1 (n = 16) | NS2 (n = 11) |
P value of: |
|
|---|---|---|---|---|---|---|
| NS vs control | NS1 vs NS2 | |||||
| WBC (cells/mm3) | <0.0001 | 0.941 | ||||
| Median | 8.0 | 2.0 | 10.0 | 8.0 | ||
| Min–max | 0–110 | 0–190 | 0–110 | 1–79 | ||
| Presence of plasma cells, % (n) | 63% (17) | 27% (19) | 50% (8) | 82% (9) | 0.001 | 0.217 |
| Protein level (g/L) (normal value: 0.15 to 0.45 g/L) | 0.021 | 0.027 | ||||
| Median | 0.48 | 0.40 | 0.52 | 0.39 | ||
| p25–p75 | 0.36–0.60 | 0.31–0.50 | 0.44–0.74 | 0.32–0.50 | ||
| Albumin quotient >QLim, % (n) | 26% (7) | 21% (15) | 38% (6) | 9% (1) | 0.611 | 0.183 |
| Total IgG index ≥0.7, % (n) | 33% (9) | 14% (10) | 56% (9) | 0% (0) | 0.031 | 0.003 |
| Intrathecal synthesis, % (n) | 48% (13) | 27% (19) | 81% (13) | 0 | 0.044 | <0.001 |
| Type II OCB, n | 7 | 12 | 7 | 0 | ||
| Type III OCB, n | 6 | 7 | 6 | 0 | ||
| Positive intrathecal anti-Treponema IgG antibody index (>1.7), % (n) | 59.3% (16) | 1.4% (1) | 81.3% (13) | 27.3% (3) | <0.001 | 0.015 |