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The entrance and exit channels of RVFV, SFTSV, LACV, and FluA polymerases. The template entry, NTP entry, template exit, and product exit channels of (A) RVFV L protein, (B) SFTSV L protein (PDB 6L42), (C) LACV L protein (PDB 6Z8K), (D) Influenza A polymerase (FluA) (PDB 6T0V) are colored in limegreen, yelloworange, salmon, and magenta, respectively. The colors of the RVFV L domains are same as those used in Fig. 2A A 40° rotated view of the RVFV L’s channels is shown inset.
