TABLE 1.
Gene Ontology (GO) analysis of Cluster A DEGs in response to 3249 strain infection at 8–13 dpi
| GO term | % associated genes/term | No. of genes | Associated genes found |
|---|---|---|---|
| Positive regulation of leukocyte activation | 5.01 | 25,00 | CCL2, CCL5, CD2, CD27, CD28, CD38, CD3E, CD4, CD40LG, CD5, CTLA4, GATA3, ICOS, IFNG, IL2RA, IL7R, IRF4, ITGAM, KLRK1, LAG3, LCK, PDCD1, TBX21, TNFRSF18, ZAP70 |
| Regulation of T cell activation | 6.55 | 23,00 | CCL2, CCL5, CD2, CD27, CD28, CD3E, CD4, CD40LG, CD5, CTLA4, GATA3, ICOS, IFNG, IL2RA, IL7R, IRF4, KLRK1, LAG3, LCK, PDCD1, TBX21, TNFRSF18, ZAP70 |
| Regulation of T cell differentiation | 8.50 | 20,00 | CCL5, CD2, CD247, CD27, CD28, CD3E, CD4, CD40LG, CD8A, CTLA4, GATA3, IFNG, IL2RA, IL7R, IRF4, LAG3, LCK, TBX21, TNFRSF18, ZAP70 |
| Lymphocyte migration | 6.61 | 16,00 | CCL2, CCL4, CCL5, CCR5, CD27, CD3E, CD4, CXCL10, FASLG, GATA3, IFNG, IL7R, KLRK1, PDCD1, TBX21, ZAP70 |
| Positive regulation of α/β T cell activation | 6.06 | 6,00 | CD28, CD3E, GATA3, IFNG, IL7R, ZAP70 |
| IL-2 receptor activity | 66.67 | 5,00 | CCR5, CD4, IL2RA, IL2RB, IL7R |
| Tolerance induction | 14.29 | 4,00 | CD3E, ICOS, IL2RA, PDCD1 |
| Regulation of endothelial cell apoptotic process | 7.84 | 4,00 | CCL2, CD40LG, FASLG, GATA3 |
| Positive regulation of leukocyte mediated cytotoxicity | 5.08 | 3,00 | ITGAM, KLRK1, LAG3 |