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. 2022 Feb 8;8:6. doi: 10.1038/s41540-022-00213-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — A heat map shows the correlation coefficients between the fasting and each time point (in minutes (min)) among individuals. The 18 glucose-responsive molecules showed a significant change after glucose ingestion was selected. Molecules are ordered by hierarchical clustering using Euclidean distance and Ward’s method. The colours and numbers on the tree diagram indicate the cluster of each molecule. The dashed line indicates the threshold for dividing the cluster. The colours assigned to the names of molecules correspond to the metabolic group (inset). Abbreviations for the molecules are follows: GIP (active), gastric inhibitory polypeptide (active); Glu glutamic acid.