Table 1.
Collection time points for each BRD biomarker with 0 h being time of disease onset
| Biomarker1 | Time point |
|---|---|
| Cortisol, h | 0, 4, 8, 24, 32, 48, 72, 96, 120, 144, 168, 192 |
| IRT, h | 0, 4, 8, 24, 32, 48, 72, 96, 120, 144, 168, 192 |
| MNT, h | 8, 24, 72, 192 |
| Substance P, h | 0, 4, 8, 24, 32, 48, 72, 96, 120, 144, 168, 192 |
| Kinematic gait analysis, h | 0, 4, 8, 24, 32, 48, 72, 96, 120, 144, 168, 192 |
| VAS, h | 0, 4, 8, 24, 32, 48, 72, 96, 120, 144, 168, 192 |
| CIS, h | 0, 4, 8, 24, 32, 48, 72, 96, 120, 144, 168, 192 |
| Computerized lung score, h | 0, 4, 8, 24, 32, 48, 72, 96, 120, 144, 168, 192 |
| Average activity, h | 0, 24, 48, 72, 96, 120, 144, 168 |
| Average rumination, h | 0, 24, 48, 72, 96, 120, 144, 168 |
| Step count, h | 0, 24, 48, 72, 96, 120, 144, 168 |
| PGEM, h | 0, 72, 192 |
| Serum amyloid A, h | 0, 4, 8, 24, 32, 48, 72, 96, 120, 144, 168, 192 |
| Rectal temperature, h | 0, 8, 24, 32, 48, 72, 96, 120, 144, 168 |
IRT, infrared thermography; MNT, mechanical nociceptive threshold; VAS, visual analog scale; CIS, clinical illness score; PGEM, prostaglandin E2 metabolites.