Table 2.

AUC values for lung scores < 10% vs. lung scores < 10% by collection time point for each biomarker

Biomarker1	Hour
	0	4	8	24	32	48	72	96	120	144	168	192
Cortisol	0.64	0.59	0.63	0.60	0.66	0.63	0.64	0.77	0.69	0.68	0.81	0.67
IRT	0.74	0.64	0.69	0.59	0.71	0.64	0.58	0.69	0.66	0.69	0.67	0.75
MNT avg			0.60	0.69			0.67					0.64
MNT percent change			0.74	0.60			0.58					0.66
Substance P	0.71	0.69	0.63	0.68	0.65	0.64	0.61	0.61	0.62	0.59	0.64	0.59
Rf stance time	0.61	0.62	0.59	0.62	0.62	0.62	0.61	0.60	0.67	0.60	0.61	0.66
Rf stride length	0.81	0.64	0.67	0.79	0.62	0.65	0.72	0.70	0.62	0.63	0.60	0.61
Rf force	0.65	0.63	0.65	0.60	0.58	0.64	0.64	0.60	0.61	0.61	0.58	0.76
Rf impulse	0.59	0.62	0.61	0.65	0.61	0.60	0.59	0.59	0.64	0.62	0.59	0.73
Rf pressure	0.62	0.64	0.62	0.65	0.62	0.56	0.61	0.68	0.61	0.72	0.64	0.74
Gait distance	0.60	0.65	0.66	0.62	0.69	0.61	0.64	0.62	0.78	0.73	0.59	0.68
Gait velocity	0.58	0.61	0.62	0.68	0.77	0.70	0.66	0.67	0.62	0.60	0.59	0.61
VAS	0.78	0.68	0.70	0.68	0.67	0.84	0.68	0.68	0.73	0.75	0.75	0.73
CIS	0.65	0.58	0.60	0.59	0.60	0.77	0.62	0.72	0.64	0.68	0.64	0.67
Computerized lung score	0.59	0.58	0.58	0.68	0.61	0.58	0.56	0.71	0.64	0.57	0.64	0.56
Average activity	0.71			0.74		0.90	0.86	0.85	0.89	0.83	0.80
Average rumination	0.63			0.58		0.81	0.68	0.68	0.73	0.68	0.69
Step count	0.74			0.64		0.84	0.80	0.83	0.80	0.84	0.74
PGEM	0.74						0.78					0.70
Serum Amyloid A	0.62	0.59	0.53	0.62	0.59	0.62	0.63	0.61	0.61	0.66	0.63	0.71
Rectal Temperature	0.72		0.69	0.78	0.63	0.90	0.82	0.66	0.61	0.57	0.66

IRT, infrared thermography; MNT, mechanical nociceptive threshold; Rf, right front; VAS, visual analog scale; CIS, clinical illness score; PGEM, prostaglandin E₂ metabolites.