TABLE 2.

Footprint residues of the monoclonal antibodies ADK9, HL2368, HL2370, HL2372, and HL2374 on the AAV9 capsid

Antibody	Contact residues	Occluded residues	Variable region
ADK9		384, 389, 391	III
	456–459	452, 460, 462	IV
	492, 494–498	488, 491, 493	V
		528–534, 545	VI
		554–556, 558–560	VII
	584, 587–589		VIII
		701–708, 712, 713	IX
		724–728, 730, 731
	HL2368		253, 256, 258–260
262–270, 273		271, 272	I
		274, 275, 278, 293, 375, 376
385–387		382–384, 389, 391	III
		438–441, 443
		446, 467–473	IV
		488, 495, 503, 510–515	V
		528–534	VI
		572, 661, 662
		703–718	IX
		722
HL2370			248, 250–255
		265–269, 271, 272	I
		332	II
		334, 363–365, 370, 371, 373, 376, 438
		438–441
	454–458	446, 448, 449, 451–453, 459, 460, 462, 464–473	IV
		491, 493, 494, 496–500, 503, 504	V
		547–560	VII
		655–676
		726	IX
HL2372		221, 228, 246–248, 250–256, 258, 291, 324, 325
	327–333		II
		334, 335, 338, 341, 365, 369–373, 376
		550	VII
	659	651–653, 655, 656, 658, 661–668, 670–674, 678
		718–720	IX
HL2374		253, 258, 259, 260, 262
		263–272	I
		273–275, 278, 376
		384–387	III
		438, 439, 440, 441
	449, 452–458	446, 448, 451, 457, 462, 464, 465, 467–473	IV
		497–501, 503–505, 506	V
		515
		529	VI
		549–553	VII
		579, 590	VIII
		661, 662, 664
		707–718