FIGURE 3 |.

Nasal complement profiles on N. meningitidis that occupy the pathogen surface under three conditions: (i) FP and FHR-3 recruitment in blue; (ii) FP and C4BP, Vn, FH, and FHL-1 recruitment in green; and (iii) FP and FHR-3, C4BP, Vn, FH, and FHL-1 recruitment in red. (A) Conditions (ii) and (iii) rapidly occupy the surface of N. meningitidis and account for 81.1 and 83.1% of its surface, respectively. Condition (i) occupies a lower percent of the bacterial surface (52.8%). (B) Conversely, condition (i) produces the highest membrane attack complex (MAC) level, occupying 6.1% N. meningitidis surface, whereas, conditions (ii) and (iii) led to lower MAC production that occupied 2.3 and 2.1% of the bacterial surface, respectively.