FIGURE 4 |.

Bloodstream time profiles on N. meningitidis under three conditions: (i) FP and FHR-3 recruitment in blue; (ii) FP and C4BP, Vn, FH, and FHL-1 recruitment in green; and (iii) FP and FHR-3, C4BP, Vn, FH, and FHL-1 recruitment in red. All three conditions rapidly occupy the bacterial surface. However, condition (i) occupied a lower amount of 84.5% of the bacterial surface. Time profile of condition (ii) is under the profile of condition (iii). Moreover, membrane attack complex (MAC) profiles in the inset show condition (i) produced the highest amount, whereas under conditions (ii) and (iii) MAC levels are lower and overlapping.