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. 2022 Feb 9;8(6):eabj7795. doi: 10.1126/sciadv.abj7795

Fig. 1. Suggested cellular vault functions, general architecture, and MVP domain organization.

Fig. 1.

(A) Schematics representing proposed vault functions related to transport of variable cargo in the cell. (B) Schematics showing two half vault particles with dimensions indicated. (C) Structure of whole vaults with one MVP monomer colored orange (PDB ID: 4HL8) with its constituent domains explicitly labeled. (D) Top: Detailed view of R1 domains located at the interface of the two half vaults. Bottom: Putative residues involved in the stabilization of the whole vault state.