TABLE 2.
Treatment outcomes of conventional endoscopic submucosal dissection (C‐ESD) and ProKnife injection ESD (P‐ESD)
| All | C‐ESD | P‐ESD | p‐value | |
|---|---|---|---|---|
| n = 68 | n = 34 | n = 34 | ||
| ESD procedure | <0.001 | |||
| Time (min) | 40 (33–51) | 46 (36.4–64.6) | 36.3 (28.4–46.8) | |
| Log‐transformed time (min) | 3.73 (0.37) | 3.88 (0.36) | 3.59 (0.32) | |
| En bloc resection, n (%) | 68 (100) | 34 (100) | 34 (100) | ‐ |
| Complete resection, n (%) | 61 (89.7) | 29 (85.3) | 32 (94.1) | 0.23 |
| Perforation, n (%) | 3 (4.4) | 1 (2.9) | 2 (5.9) | 0.55 |
| Operator's change, n (%) | 9 (13.2) | 5 (14.7) | 4 (11.8) | 0.72 |
| Assist‐technique usage | 0 (0) | 0 (0) | 0 (0) | ‐ |
| Number of injections | 5.5 (4–9) | 4 (3–5) | 7.5 (6–10) | <0.001 |
| Rescue injection, n (%) | ‐ | ‐ | 7 (20.6) | ‐ |
| Total volume of injective solutions (ml) | 23 (18.3–29) | 27.5 (20–31.5) | 20 (16–26.3) | 0.0019 |
| Circumferential length (mm) | 113.9 (103.0–127.6) | 112.2 (102.2–128.4) | 114.2 (103.3–128.0) | 0.60 |
| Resected specimen size (mm2) | 989.1 (830.5–1271.7) | 971.8 (821.5–1285.8) | 997.0 (835.2–1278.8) | 0.71 |
| Mucosal incision | ||||
| Time (min) | 17.5 (13.1–22.0) | 21.3 (16–25.4) | 16 (12–19) | 0.0014 |
| Speed (mm/min) | 6.6 (5.2–8.6) | 5.4 (4.5–7.4) | 7.4 (6.3–9.4) | 0.0011 |
| Submucosal dissection | ||||
| Time (min) | 22.5 (16.6–30.9) | 25.3 (18.9–41.4) | 19.5 (16–28.5) | 0.023 |
| Speed (mm2/min) | 41.5 (32.7–60.4) | 36.4 (27.2–50.9) | 49.9 (38.3–63.1) | 0.006 |
Values are presented as median (interquartile range) or frequency (%).
Log‐transformed time are presented as mean (standard deviation).
Abbreviations: C‐ESD, conventional ESD; P‐ESD, ProKnife injection ESD.