TABLE 3.
Univariate and Multivariate analysis for the factors associated with the difficulty of endoscopic submucosal dissection (ESD) including long procedure time (≥50 min), operator change, and perforation
| Univariate | Multivariate | |||||||
|---|---|---|---|---|---|---|---|---|
| No. of Patients | No. of events | OR | 95% CI | p‐value | OR | 95% CI | p‐value | |
| Location | ||||||||
| Lower | 32 | 7 | 1 | Ref | 0.053 | 1 | Ref | 0.051 |
| Upper or middle | 36 | 16 | 2.9 | 0.98–8.3 | 3.34 | 0.96–11.7 | ||
| Position | ||||||||
| L or A or P | 39 | 10 | 1 | Ref | 0.10 | 1 | Ref | 0.10 |
| G | 29 | 13 | 2.4 | 0.84–6.6 | 2.7 | 0.82–8.8 | ||
| Estimated size | ||||||||
| <950 mm 2 | 48 | 14 | 1 | Ref | 0.21 | 1 | Ref | 0.27 |
| ≥950 mm 2 | 20 | 9 | 2.0 | 0.68–5.8 | 2.1 | 0.56–7.9 | ||
| Operator skill | ||||||||
| ≥50 cases | 31 | 6 | 1 | Ref | 0.024 | 1 | Ref | 0.022 a |
| 0–49 cases | 37 | 17 | 3.5 | 1.2–10.6 | 3.9 | 1.16–13.4 | ||
| Method | ||||||||
| P‐ESD | 33 | 8 | 1 | Ref | 0.076 | 1 | Ref | 0.029 a |
| C‐ESD | 33 | 15 | 2.6 | 0.90–7.3 | 3.8 | 1.1–13.0 | ||
a
significant value
Abbreviations: A, anterior wall; C‐ESD, conventional ESD; CI, confidence interval; ESD, endoscopic submucosal dissection; G, greater curvature; L, lessor curvature; OR, odds ratio; P, posterior wall; P‐ESD, ProKnife injection ESD.