TABLE 4.
Author, year | Study population | No. of cases | No. of events (rate) | Type of thromboembolic event | Status of AT agents in cases with event |
---|---|---|---|---|---|
Lim et al., 2012 80 | All patients | 1503 | 1 (0.07%) | Cerebral infarction | Discontinuation of antiplatelet agents |
Takeuchi et al., 2013 94 | All patients | 833 | 1 (0.12%) | Cerebral infarction | Discontinuation of AT agent (detail unclear) |
Yoshio et al., 2013 93 | All patients | 1250 | 1 (0.08%) | Cerebral infarction | Discontinuation of aspirin, P2Y12 receptor antagonist, and cilostazol with heparin bridging |
Sanomura et al., 2014 92 | Patients on aspirin | 78 | 4 (5.1%) | 2, cerebral infarction; 2, myocardial infarction | All, discontinuation of aspirin |
Igarashi et al., 2017 91 | Patients on AT agents | 367 | 4 (1.1%) | 2, cerebral infarction; 1, TIA; 1, angina pectoris | All, discontinuation of antiplatelet agents |
Shiroma et al., 2021 90 | All patients | 10,320 | 3 (0.03%) | 2, cerebral infarction; 1, TIA | 1, discontinuation of warfarin; 1, discontinuation of warfarin with heparin bridging; 1, continuation of DOAC with heparin bridging |
Abbreviations: AT, antithrombotic; DOAC, direct oral anticoagulant; TIA, transient ischemic attack.