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. 2005 Mar 18;14(Suppl I):S18–S25. doi: 10.2188/jea.14.S18

Table 2. Relative risks (RR) of all-cause mortality according to alcohol consumption in men and women..

Past drinkers Never drinkers Current drinkers (g alcohol per day) P for trend
Men All <22.8 22.8-45.5 45.6-68.3 ≥68.4
 
 Person-years 14,449 33,927 163,850 49,621 39,212 47,355 27,662
 No. of death 187 175 973 238 229 286 220
 Age-adjusted RR 2.16 (1.76 - 2.66) 1.00 1.29 (1.10 - 1.52) 1.07 (0.88 - 1.30) 1.22 (1.00 - 1.48) 1.26 (1.04 - 1.52) 1.92 (1.57 - 2.34) <0.001
 Multivariate RR1 1.86 (1.50 - 2.29) 1.00 1.21 (1.03 - 1.43) 1.10 (0.90 - 1.33) 1.17 (0.96 - 1.42) 1.16 (0.96 - 1.40) 1.62 (1.32 - 1.99) <0.001
 Multivariate RR2 1.86 (1.48 - 2.34) 1.00 1.21 (1.01 - 1.43) 1.09 (0.88 - 1.35) 1.14 (0.92 - 1.42) 1.20 (0.97 - 1.47) 1.59 (1.27 - 1.98) <0.001
 
Women All <22.8 ≥22.8
 
 Person-years 7,514 138,963 45,465 39,879 5,586
 No. of death 36 400 108 78 30
 Age-adjusted RR 1.78 (1.27 - 2.51) 1.00 1.09 (0.88 - 1.35) 0.90 (0.70 - 1.15) 2.43 (1.67 - 3.53) <0.001
 Multivariate RR1 1.40 (0.98 - 2.00) 1.00 1.01 (0.81 - 1.27) 0.87 (0.68 - 1.12) 1.98 (1.33 - 2.95)  0.005
 Multivariate RR2 1.33 (0.88 - 2.00) 1.00 1.12 (0.88 - 1.43) 0.98 (0.75 - 1.28) 2.10 (1.36 - 3.24)  0.005

† : Adjusted for age in years; education (up to 15 years of age, 16-18, or 19 years or older); marital status at baseline (whether or not living with spouse); past histories of hypertension, renal diseases, liver diseases, diabetes mellitus, peptic ulcers, or tuberculosis; cigarette smoking (never smokers, past smokers, current smokers smoking 1-19 cigarettes per day, or current smokers smoking at least 20 cigarettes per day); body mass index in kg/m2 (less than 18.5, 18.5-24.9, or 25.0 or higher); walking time per day (less than 1 hour, or 1 hour or longer); consumption frequencies of green vegetables and oranges (almost daily, 3-4 times per week, 1-2 times per week, or 1-2 times per month or less often). Multivariate RR2 has been estimated with the exclusion of 317 subjects (220 men and 97 women) who died within the first 3 years of follow-up. Numbers in parentheses are 95% confidence intervals.