Table 3. Relative risks (RR) of all-cause mortality according to alcohol consumption by age classes in men.†.
Past drinkers | Never drinkers | Current drinkers (g alcohol per day) | P for trend | |||||
| ||||||||
All | <22.8 | 22.8-45.5 | 45.6-68.3 | ≥68.4 | ||||
40-49 years old | ||||||||
Person-years | 3,890 | 13,189 | 75,076 | 23,802 | 16,929 | 20,171 | 14,175 | |
No. of death | 23 | 17 | 208 | 58 | 44 | 49 | 57 | |
Age-adjusted RR | 4.62 (2.47 - 8.64) | 1.00 | 2.16 (1.31 - 3.53) | 1.90 (1.10 - 3.26) | 2.02 (1.15 - 3.54) | 1.89 (1.09 - 3.27) | 3.14 (1.82 - 5.39) | <0.001 |
Multivariate RR1 | 3.60 (1.90 - 6.82) | 1.00 | 2.10 (1.27 - 3.45) | 1.97 (1.14 - 3.39) | 2.01 (1.14 - 3.53) | 1.83 (1.05 - 3.19) | 2.74 (1.58 - 4.76) | 0.001 |
Multivariate RR2 | 3.50 (1.72 - 7.12) | 1.00 | 2.20 (1.27 - 3.81) | 2.00 (1.10 - 3.64) | 2.05 (1.11 - 3.82) | 1.98 (1.08 - 3.65) | 2.97 (1.63 - 5.42) | <0.001 |
50-59 years old | ||||||||
Person-years | 6,022 | 12,784 | 60,136 | 17,420 | 14,565 | 17,915 | 10,238 | |
No. of death | 75 | 72 | 427 | 106 | 98 | 119 | 104 | |
Age-adjusted RR | 2.23 (1.61 - 3.08) | 1.00 | 1.26 (0.98 - 1.62) | 1.08 (0.80 - 1.46) | 1.20 (0.88 - 1.62) | 1.18 (0.88 - 1.58) | 1.81 (1.34 - 2.45) | <0.001 |
Multivariate RR1 | 1.82 (1.30 - 2.53) | 1.00 | 1.20 (0.94 - 1.55) | 1.14 (0.84 - 1.54) | 1.16 (0.86 - 1.58) | 1.12 (0.83 - 1.50) | 1.50 (1.10 - 2.04) | 0.019 |
Multivariate RR2 | 1.84 (1.28 - 2.65) | 1.00 | 1.15 (0.87 - 1.52) | 1.11 (0.80 - 1.54) | 1.14 (0.81 - 1.59) | 1.08 (0.78 - 1.50) | 1.34 (0.95 - 1.90) | 0.114 |
60 years old or older | ||||||||
Person-years | 4,537 | 7,954 | 28,637 | 8,399 | 7,718 | 9,270 | 3,250 | |
No. of death | 89 | 86 | 338 | 74 | 87 | 118 | 59 | |
Age-adjusted RR | 1.83 (1.36 - 2.47) | 1.00 | 1.09 (0.86 - 1.38) | 0.81 (0.60 - 1.11) | 1.04 (0.77 - 1.40) | 1.18 (0.89 - 1.56) | 1.69 (1.21 - 2.35) | <0.001 |
Multivariate RR1 | 1.59 (1.17 - 2.15) | 1.00 | 1.02 (0.80 - 1.30) | 0.82 (0.60 - 1.12) | 0.99 (0.73 - 1.34) | 1.08 (0.81 - 1.43) | 1.46 (1.04 - 2.05) | 0.003 |
Multivariate RR2 | 1.61 (1.16 - 2.25) | 1.00 | 1.06 (0.82 - 1.38) | 0.86 (0.61 - 1.21) | 0.95 (0.68 - 1.33) | 1.17 (0.86 - 1.58) | 1.51 (1.05 - 2.18) | 0.002 |
† : Adjusted for education (up to 15 years of age, 16-18, or 19 years or older); marital status at baseline (whether or not living with spouse); past histories of hypertension, diabetes mellitus, renal diseases, liver diseases, peptic ulcers, or tuberculosis; cigarette smoking (never smokers, past smokers, current smokers smoking 1-19 cigarettes per day, or current smokers smoking at least 20 cigarettes per day); body mass index in kg/m2 (less than 18.5, 18.5-24.9, or 25.0 or higher); walking time per day (less than 1 hour, or 1 hour or longer); consumption frequencies of green vegetables and oranges (almost daily, 3-4 times per week, 1-2 times per week, or 1-2 times per month or less often). Multivariate RR2 has been estimated with the exclusion of 220 subjects who died within the first 3 years of follow-up. Numbers in parentheses are 95% confidence intervals.