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. 2005 Mar 18;14(Suppl I):S18–S25. doi: 10.2188/jea.14.S18

Table 3. Relative risks (RR) of all-cause mortality according to alcohol consumption by age classes in men..

Past drinkers Never drinkers Current drinkers (g alcohol per day) P for trend

All <22.8 22.8-45.5 45.6-68.3 ≥68.4
40-49 years old
 Person-years 3,890 13,189 75,076 23,802 16,929 20,171 14,175
 No. of death 23 17 208 58 44 49 57
 Age-adjusted RR 4.62 (2.47 - 8.64) 1.00 2.16 (1.31 - 3.53) 1.90 (1.10 - 3.26) 2.02 (1.15 - 3.54) 1.89 (1.09 - 3.27) 3.14 (1.82 - 5.39) <0.001
 Multivariate RR1 3.60 (1.90 - 6.82) 1.00 2.10 (1.27 - 3.45) 1.97 (1.14 - 3.39) 2.01 (1.14 - 3.53) 1.83 (1.05 - 3.19) 2.74 (1.58 - 4.76)  0.001
 Multivariate RR2 3.50 (1.72 - 7.12) 1.00 2.20 (1.27 - 3.81) 2.00 (1.10 - 3.64) 2.05 (1.11 - 3.82) 1.98 (1.08 - 3.65) 2.97 (1.63 - 5.42) <0.001
 
50-59 years old
 Person-years 6,022 12,784 60,136 17,420 14,565 17,915 10,238
 No. of death 75 72 427 106 98 119 104
 Age-adjusted RR 2.23 (1.61 - 3.08) 1.00 1.26 (0.98 - 1.62) 1.08 (0.80 - 1.46) 1.20 (0.88 - 1.62) 1.18 (0.88 - 1.58) 1.81 (1.34 - 2.45) <0.001
 Multivariate RR1 1.82 (1.30 - 2.53) 1.00 1.20 (0.94 - 1.55) 1.14 (0.84 - 1.54) 1.16 (0.86 - 1.58) 1.12 (0.83 - 1.50) 1.50 (1.10 - 2.04)  0.019
 Multivariate RR2 1.84 (1.28 - 2.65) 1.00 1.15 (0.87 - 1.52) 1.11 (0.80 - 1.54) 1.14 (0.81 - 1.59) 1.08 (0.78 - 1.50) 1.34 (0.95 - 1.90)  0.114
 
60 years old or older
 Person-years 4,537 7,954 28,637 8,399 7,718 9,270 3,250
 No. of death 89 86 338 74 87 118 59
 Age-adjusted RR 1.83 (1.36 - 2.47) 1.00 1.09 (0.86 - 1.38) 0.81 (0.60 - 1.11) 1.04 (0.77 - 1.40) 1.18 (0.89 - 1.56) 1.69 (1.21 - 2.35) <0.001
 Multivariate RR1 1.59 (1.17 - 2.15) 1.00 1.02 (0.80 - 1.30) 0.82 (0.60 - 1.12) 0.99 (0.73 - 1.34) 1.08 (0.81 - 1.43) 1.46 (1.04 - 2.05)  0.003
 Multivariate RR2 1.61 (1.16 - 2.25) 1.00 1.06 (0.82 - 1.38) 0.86 (0.61 - 1.21) 0.95 (0.68 - 1.33) 1.17 (0.86 - 1.58) 1.51 (1.05 - 2.18)  0.002

† : Adjusted for education (up to 15 years of age, 16-18, or 19 years or older); marital status at baseline (whether or not living with spouse); past histories of hypertension, diabetes mellitus, renal diseases, liver diseases, peptic ulcers, or tuberculosis; cigarette smoking (never smokers, past smokers, current smokers smoking 1-19 cigarettes per day, or current smokers smoking at least 20 cigarettes per day); body mass index in kg/m2 (less than 18.5, 18.5-24.9, or 25.0 or higher); walking time per day (less than 1 hour, or 1 hour or longer); consumption frequencies of green vegetables and oranges (almost daily, 3-4 times per week, 1-2 times per week, or 1-2 times per month or less often). Multivariate RR2 has been estimated with the exclusion of 220 subjects who died within the first 3 years of follow-up. Numbers in parentheses are 95% confidence intervals.