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Acute Cardiac Injury in Coronavirus Disease 2019
In the acute setting, both direct (viral) and indirect (immune-mediated) damage to the myocardial and other heart tissues can give rise to perimyocarditis or myocarditis. Moreover, endothelial tissue injury, by means of endotheliitis and microthrombus formation, leads to type 2 myocardial infarction. TF = tissue factor; TNF= tumor necrosis factor; other abbreviations as in Figure 1.
