Table 1.
Univariate analysis of the relationship between medical information and central CLNM.
| Medical information | Lymph node metastasis | χ2 | P | |
|---|---|---|---|---|
| Yes (n =112) | No (n = 184) | |||
| Age (year) | 5.731 | 0.022 | ||
| ≤40 | 69 (44.23) | 87 (55.87) | ||
| >40 | 43 (30.71) | 97 (69.29) | ||
| Gender | 3.329 | 0.074 | ||
| female | 77 (34.84) | 144 (65.16) | ||
| male | 35 (46.67) | 40 (53.33) | ||
| Tumor size (cm) | 25.027 | <0.001 | ||
| ≤1.0 | 57 (28.22) | 145 (71.78) | ||
| >1.0 | 55 (58.51) | 39 (41.49) | ||
| Aspect ratio | 2.069 | 0.179 | ||
| <1 | 76(35.35) | 139 (64.65) | ||
| ≥1 | 36 (44.44) | 45 (55.56) | ||
| Tumor location | 0.142 | 0.931 | ||
| left | 45 (37.82) | 74 (62.18) | ||
| right | 62 (38.27) | 100 (61.73) | ||
| isthmic | 5 (33.33) | 10 (66.67) | ||
| Capsule contact | 13.295 | <0.001 | ||
| present | 100 (43.29) | 131 (56.71) | ||
| absent | 12 (18.46) | 53 (81.54) | ||
| Microcalcifications | 21.279 | <0.001 | ||
| absent | 36 (24.66) | 110 (75.34) | ||
| present | 76 (50.67) | 74 (49.33) | ||
| Boundary | 1.226 | 0.306 | ||
| unclear | 80 (40.00) | 120 (60.00) | ||
| clear | 32 (33.33) | 64 (66.67) | ||
| Morphology | 2.223 | 0.195 | ||
| Irregular | 106 (39.11) | 165 (60.89) | ||
| regular | 6 (24.00) | 19 (76.00) | ||
| Low echo | 0.985 | 0.322 | ||
| no | 20 (44.44) | 25 (55.56) | ||
| yes | 92 (36.65) | 159 (63.35) | ||
| BRAFV600E | 4.839 | 0.038 | ||
| Mutation | 101 (37.55) | 168 (62.45) | ||
| Wild | 11 (40.74) | 16 (59.26) | ||
| Blood flow signal | 4.782 | 0.033 | ||
| poor | 31 (29.52) | 74 (70.48) | ||
| rich | 81 (42.41) | 110 (57.59) | ||
| TSH | 1.356 | 0.342 | ||
| negative | 106 (37.20) | 179 (62.80) | ||
| high | 6 (54.54) | 5 (45.46) | ||
| Tg | 0.555 | 0.758 | ||
| low | 15 (39.47) | 23 (60.53) | ||
| normal | 88 (36.97) | 150 (63.03) | ||
| high | 9 (45.00) | 11 (55.00) | ||
| TgAb | 5.103 | 0.033 | ||
| positive | 29 (50.88) | 28 (49.12) | ||
| negative | 83 (34.73) | 156 (65.27) | ||
| TPOAb | 2.899 | 0.100 | ||
| positive | 28 (47.46) | 31 (52.54) | ||
| negative | 84 (35.44) | 153 (64.56) | ||
Thyroid function tests feature: TSH (reference: 0.35–5.00 μIU/ml), TgAb (reference: 0.00–115.00 IU/ml), TPOAb (reference: 0.00–34.00 IU/ml), Tg (reference: 1.40–78.00 μg/L).