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Number of docks with binding energy greater than the median binding energy for wildtype kinase per inhibitor.
| Entrectinib | Crizotinib | Lorlatinib | Repotrectinib | |
|---|---|---|---|---|
| Wildtype DFG-in | 589 of 1120 | 484 of 1118 | 864 of 1120 | 700 of 1120 |
| Wildtype DFG-out | 532 of 1188 | 1116 of 2078 | 716 of 2080 | 900 of 2080 |
| F2004C DFG-in | 209 of 638 | 292 of 638 | 459 of 640 | 426 of 640 |
| F2004C DFG-out | 90 of 640 | 180 of 478 | 122 of 480 | 138 of 480 |
