Table 7.
Test name | N studies | N CFS | N controls | Hedges'g | S.E | 95% CI | p value | Q | p | I2 (%) | Study references |
---|---|---|---|---|---|---|---|---|---|---|---|
Visual modality | |||||||||||
Spatial span forward | 2 | 71 | 40 | − 0.55 | 0.20 | − 0.952 to − 0.151 | 0.007 | 2.03 | 0.15 | 50.64 | Joyce et al.29, Robinson et al.44 |
Spatial working memory (between search errors) | 2 | 101 | 157 | 0.26 | 0.13 | 0.012–0.514 | 0.04 | 0.00 | 0.94 | 0.00 | Capuron et al.13, Majer et al.33 |
Spatial working memory (strategy score) | 2 | 101 | 157 | 0.36 | 0.13 | 0.105–0.609 | 0.006 | 3.28 | 0.07 | 69.50 | Capuron et al.13, Majer et al.33 |
Verbal modality | |||||||||||
Digit span backward | 8 | 251 | 195 | − 0.37 | 0.10 | − 0.566 to − 0.182 | 0.0001 | 24.50 | 0.00 | 71.43 | De Luca et al.22, Fiedler et al.24, Lawrie et al.31, Michiels et al.39, Neu et al.42, Robinson et al.44, Tiersky et al.52, Vercoulen et al.54 |
Digit span forward | 11 | 359 | 261 | − 0.23 | 0.08 | − 0.387 to − 0.064 | 0.006 | 7.64 | 0.66 | 0.00 | Claypoole et al.15, De Luca et al.22, Fiedler et al.24, Lawrie et al.31, Marcel et al.34, Michiels et al.39, Neu et al.42, Robinson et al.44, Smith et al.51, Tiersky et al.52, Vercoulen et al.54 |
ME/CFS myalgic encephalomyelitis/chronic fatigue syndrome, N number.