Table 2.
Human papillomavirus (HPV) seroprevalence to HPV-genotype 6, 11, 16, 18 and 45 in the offspring at the age of 12-, 24, and 36 months born to the mothers seronegative for the respective HPV-genotype.
| Follow up visit | 12 months | 24 months | 36 months | |||
|---|---|---|---|---|---|---|
| HPV antibodies in sera | Seropositive infants (n) mean MFI ± SD |
Infants seropositive for the same HPV type at two visits (n) | Infants seropositive for the same HPV type at three visits (n) | Total number of HPV-seropositive offspring at the 12-, 24-, and 36-month FU-visits born to 109 HPV-seronegative mothers | ||
| HPV6 |
9 1152 ± 1033 |
10 1167 ± 954 |
16 642 ± 364 |
10 | 3 | 19 |
| HPV11 |
7 498 ± 330 |
12 360 ± 150 |
3 293 ± 57 |
3 | 19 | |
| HPV16 |
3 276 ± 66 |
5 397 ± 252 |
1 549 |
3 | 6 | |
| HPV18 |
4 475 ± 260 |
14 417 ± 233 |
3 624 ± 445 |
2 | 3 | 13 |
| HPV45 | 0 |
1 561 |
0 | 1 | ||
| Total HPV-sero-positivity at the given age | 23 | 42 | 23 | 18 | 6 | In total, 53% (58/109) |
The cut-off for seropositivity was ≥ 200 MFI.