Structure of Pseudomonas aeruginosa AlgL reveals an elongated, highly conserved, and strongly electropositive groove.A, electrostatic surface representation of AlgL calculated by APBS Tools; contoured from +5 (blue) to −5 (red) kT/e (102). B, conservation surface representation of AlgL calculated by the ConSurf server; green indicates residues that are less conserved, and purple indicates residues that are highly conserved (103). C, AlgL in complex with a mannuronate residue (yellow) reveals a partially enclosed structure.